Deplin® enables anti-depressants to be more effective. : Deplin®

A First Choice Depression Augmentation

Dietary management of depression with Deplin^® regulates all 3 monoamine neurotransmitters associated with mood by providing the increased requirements for folate in the brain.

	L-methylfolate is needed by depressed patients with suboptimal folate to regulate the synthesis of monoamines (serotonin, norepinephrine and dopamine) and known as a trimonoamine modulator (TMM).^{1, 2}
	By managing trimonoamine neurotransmitter synthesis, L-methylfolate, when taken with antidepressants, improves benefits.^{1, 2}

Deplin^® (7.5mg L-methylfolate) is a prescription medical food for the dietary management of suboptimal folate levels in depressed patients.