Deplin® contains 7.5 mg of L-methylfolate, the only active form of folate that can cross the blood brain barrier.
L-methylfolate crosses the blood brain barrier and aids in the synthesis of new neurotransmitters (brain chemicals) associated with mood.

Normalizing neurotransmitters, serotonin, norepinephrine, and dopamine enables your antidepressant to work better.
Deplin® is the first medical food product indicated for the distinct nutritional requirements of persons with low plasma and/or low red blood cell folate with particular emphasis for those individuals who have a major depressive disorder that has not fully responded or may not fully respond to antidepressant therapy.