Folic acid is a man-made product that needs to be broken down by the body through a lengthy 4-step process. Folate that comes from your diet (e.g green vegetables) needs to undergo a 3-step transformation.
Deplin® is able to be used immediately upon absorption.
Over one half of the general population is compromised in it's ability to break down folic acid into L-methylfolate (MTHFR C->T polymorphs) and is even higher in people who suffer from depression15, 16.
Deplin® is unaffected by this common impairment in the body's ability to break down folic acid.
One Deplin® 7.5mg tablet is bioequivalent to taking sixty-six 800 mcg folic acid pills17.
Deplin® is the first medical food product indicated for the distinct nutritional requirements of persons with low plasma and/or low red blood cell folate with particular emphasis for those individuals who have a major depressive disorder that has not fully responded or may not fully respond to antidepressant therapy.