Deplin® vs. Folic Acid

Folic acid is a man-made product that needs to be broken down by the body through a lengthy 4-step process. Folate that comes from your diet (e.g green vegetables) needs to undergo a 3-step transformation.

Deplin® is able to be used immediately upon absorption.10

Deplin® vs. Folic Acid

Over one half of the general population is compromised in its ability to break down folic acid into L-methylfolate (MTHFR C->T polymorphs) and is even higher in people who suffer from depression.12, 13

Deplin® is unaffected by this common impairment in the body's ability to break down folic acid.

One Deplin® 7.5mg tablet is bioequivalent to taking sixty-six 800 mcg folic acid pills.14

What To Expect »


Deplin® (7.5mg or 15mg L-methylfolate) is a prescription medical food for the dietary management of suboptimal folate levels in depressed patients.

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