The Active Folate in DEPLIN® Is Different From Folic Acid

Over-the-counter (OTC) folic acid needs to be activated by your body before it can be used. Unfortunately, up to 70% of people with depression may have a compromised ability to complete this activation.

DEPLIN® capsules can provide you with already-active folate so your body does not have to activate it for you to see a benefit. DEPLIN® addresses the body’s nutritional requirements and creates an environment that allows you to get the most out of your antidepressant therapy.

DEPLIN® helps your antidepressant work better

The active folate in DEPLIN® capsules may help boost the production of natural chemicals in the brain that may affect mood.

In a healthy brain, mood is controlled by the presence of natural chemicals called neurotransmitters. In people with depression, the brain may not make enough neurotransmitters. This may be due to low levels of active folate in the brain. An antidepressant can ease depression symptoms by preventing the reabsorption of neurotransmitters, increasing the availability of neurotransmitters in the brain. The active folate in DEPLIN® helps boost the body’s ability to produce neurotransmitters so you can get the most from your antidepressant therapy.


Is DEPLIN® Right for You?

Is DEPLIN® Right for You?

Learn about how you may benefit from adding DEPLIN® to your antidepressant medication.


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DEPLIN® is a medical food for use only under medical supervision for the clinical dietary management of depression and schizophrenia and is specially formulated to meet the distinctive nutritional requirement for this condition.

Manufactured and Distributed by:
Alfasigma USA, Inc.
Shreveport, LA 71104
© 2023 Alfasigma USA, Inc.


Deplin® capsules are now free from dyes.
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